Objective To explore the research progress of ciguatoxin， understand the current research status and development trends both domestically and internationally.Methods Based on the Web of Science （WoS） core collection database and the China National Knowledge Infrastructure （CNKI） ciguatoxin research literature， CiteSpace 6.3.1 software was used to construct a visual scientific knowledge map for bibliometric analysis.Results The overall number of studies on ciguatoxin both domestically and internationally shows a fluctuating trend every year. The main research teams abroad come from universities and research institutes in Japan， the United States， and other countries. Countries such as Australia and France play an important linking role. Within China， the leading research entities include universities and research institutes such as Shenzhen Center for Disease Control and Prevention and Guangdong University of Technology. Domestic and foreign researchers mostly conduct group research， although inter-group collaboration within China remains somewhat limited. As research into ciguatoxin advances， the research hotspots have changed accordingly， including dinoflagellates， ciguatoxin poisoning， gene regulation， and so on.Conclusion This study provides a reference basis for understanding the current status and development trends of ciguatoxin research.