云南省市售天麻中常见风险因子污染分析及膳食暴露风险评估
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1.云南省公共卫生与生物安全重点实验室,云南省疾病预防控制中心(云南省预防医学科学院),云南 昆明 650022;2.浙江清华长三角研究院,浙江 嘉兴 314006;3.国家食品安全风险评估中心,中国医学科学 食品安全创新单元,国家卫生健康委员会食品安全风险评估重点实验室,北京 100022

作者简介:

董海燕 女 副主任医师 研究方向为营养与食品安全 E-mail:59745519@qq.com

通讯作者:

包汇慧 女 研究员 研究方向为食品安全与风险评估 E-mail:baohuihui@cfsa.net.cn
刘志涛 男 主任医师 研究方向为营养与食品安全 E-mail:156423746@qq.com

中图分类号:

R155

基金项目:

国家重点研发计划资助(2023YFF1103804);国家食品安全风险评估中心高层次人才队伍建设项目


Analysis of common risk factors and dietary exposure of Gastrodia elata B1. sold in Yunnan Province
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1.Yunnan Provincial Key Laboratory of Public Health and Biosafety, Yunnan Center for Disease Control and Prevention (Yunnan Provincial Academy of Preventive Medical Sciences), Yunnan Kunming 650022, China;2.Yangtze Delta Region Institute of Tsinghua University, Zhejiang Jiaxing 314006, China;3.China National Center for Food Safety Risk Assessment, Chinese Academy of Medical Sciences, NHC Key Laborarory of Food Safety Risk Assessment, Beijing 100022, China

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    摘要:

    目的 了解云南省市售天麻中常见风险因子污染水平,评估其膳食暴露水平和健康风险。方法 利用2021年天麻风险监测数据、2017年天麻主产区消费量调查数据,采用单因子污染指数和内梅罗综合污染指数反映风险因子的污染程度。采用概率评估方法,计算食用天麻常见风险因子的暴露水平,包括重金属(铅、镉、汞、砷、铬)、二氧化硫和农药残留(苯醚甲环唑、丙环唑、腐霉利、甲霜灵、咪鲜胺、联苯菊酯、氯氟氰菊酯),综合考虑污染物的总膳食暴露水平,参考国际食品法典委员会认定对膳食总暴露贡献显著的情形,依据相应健康指导值占比或基准剂量评估其潜在健康风险。结果 天麻中常见重金属和农药残留总体污染水平均较低。普通人群食用天麻导致的镉、总铬、总汞和二氧化硫平均暴露量占健康指导值比值均低于5%;镉的高暴露量(P95暴露量)占健康指导值比值为8.88%;铅的平均暴露水平、总砷的平均暴露水平和高暴露水平MOE值均大于20,铅的高暴露水平MOE值小于20,需引起关注。在急性暴露情况下,因食用天麻导致的苯醚甲环唑、甲霜灵和咪鲜胺急性暴露量占ARfD值分别为0.02%、0.01%和0.01%;慢性暴露评估结果显示,7种农药的一般人群暴露水平和高消费人群暴露水平占健康指导值比例均低于5%,健康风险相对较低。结论 一般情况下,因食用天麻暴露的铅、镉、总铬、总砷、总汞及农药残留对食用人群造成的健康风险较低,需关注天麻高暴露人群镉和铅的健康风险。

    Abstract:

    Objective To analyze the pollution levels of common risk factors in Gastrodia elata B1. sold in Yunnan province, and to evaluate its dietary exposure levels and health risks.Methods Using the risk monitoring data of Gastrodia elata B1. in 2021 and the consumption survey data from the main production areas of Gastrodia elata B1. in 2017. Single factor pollution index and Nemero comprehensive pollution index were used to reflect the pollution levels of risk factors. Probability evaluation method was used to calculate the exposure levels of common risk factors in Gastrodia elata B1, including heavy metals(lead, cadmium, mercury, arsenic, chromium), sulfur dioxide, and pesticide residues (difenoconazole, propiconazole, procymidone, metalaxyl, prochloraz, bifenthrin, cyhalothrin). The total dietary exposure levels of contaminants were comprehensively considered, referencing the Codex Alimentarius Commission’s identification of significant contributions to total dietary exposure. The potential health risks were assessed .based on the proportion of corresponding health guidance values or benchmark doses.Results The overall pollution levels of common heavy metals and pesticide residues in Gastrodia elata B1. were relatively low. The average exposure levels of cadmium, total chromium, total mercury, and sulfur dioxide caused by the consumption of Gastrodia elata B1. by the general population are all less than 5% of the health guidance values; The high exposure level (P95 value) of cadmium accounted for 8.88% of the health guidance value; MOE values for both the general exposure level of lead,the general and high exposure level of total arsenic were greater than 20. However, the MOE of high exposure level of lead was less than 20, which health risk requires attention. Under acute exposure conditions, The ARfD values of acute exposure to difenoconazole, metalaxyl and prochloraz caused by consuming Gastrodia elata B1. were 0.02%, 0.01%, and 0.01%, respectively; The results of chronic exposure assessment showed that the exposure levels of the general population and high consumption population to the seven pesticides accounted for less than 5% of the health guidance values, indicating relatively low health risks.Conclusion In general, the health risks to the consumer population caused by exposure to lead, cadmium, total chromium, total arsenic, total mercury, and pesticides from consuming Gastrodia elata B1. are relatively low;In high exposure situations, attention should be paid to the health risks of cadmium and lead.

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董海燕,许晓辉,张磊,胡文敏,陈留萍,朱晓,阮元,苏玮玮,赵晓慧,蔡强,闵向东,包汇慧,刘志涛.云南省市售天麻中常见风险因子污染分析及膳食暴露风险评估[J].中国食品卫生杂志,2025,37(1):60-69.

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  • 收稿日期:2024-07-02
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  • 在线发布日期: 2025-05-16
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