进口罐头食品中呋喃及甲基呋喃污染特征及膳食暴露评估
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1.国家食品安全风险评估中心;2.浙江省疾病预防控制中心

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国家重点研发计划(2018YFC1603600)


Furan and methylfuran contamination characteristics and dietary exposure assessment of imported canned food
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1.China National Center for Food Safety Risk Assessment;2.Zhejiang Provincial Center for Disease Control and Prevention

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    摘要:

    目的 了解我国进口罐头食品中呋喃及甲基呋喃的污染特征,并评估我国人群经进口罐头暴露呋喃的健康风险。方法 基于方便抽样法,于2022年采集58份市售进口罐头食品,采用同位素稀释-顶空气相色谱-质谱法测定呋喃的含量,结合2018~2020年中国居民食品消费量,通过简单分布评估方法,开展膳食暴露风险评估。结果 在罐头肉制品中呋喃、2-甲基呋喃和3-甲基呋喃检出率分别为50%、100%和87.5%,对应的平均含量分别为5.0 ug/kg、10.8 ug/kg和3.6 ug/kg;在罐头鱼制品中,呋喃、2-甲基呋喃、3-甲基呋喃和2,5-二甲基呋喃检出率分别为100%、100%、100%和6%,对应的平均含量分别为37.4 ug/kg、52.4 ug/kg、11.1 ug/kg和2.5 ug/kg。3岁以上人群经罐头食品呋喃暴露量为0.4 ng/kg bw/d,呋喃及甲基呋喃联合暴露量为 1.1 ng/kg bw/d;消费人群经罐头食品呋喃平均暴露量为18.5 ng/kg bw/d,P95暴露水平为54.6 ng/kg bw/d;呋喃及甲基呋喃联合暴露平均水平为 52.4 ng/kg bw/d,P95暴露水平为150.8 ng/kg bw/d。对于呋喃非致癌效应的风险,各年龄组暴露边界(MOE)值范围为83920~279494;对于呋喃致癌风险,各年龄组 MOE 值范围为1717733~5720890。结论 我国人群经进口罐头食品呋喃膳食暴露健康风险较低。

    Abstract:

    Objective To investigate the contamination characteristics of furan and methylfuran in imported canned food and to evaluate the dietary exposure risk of furan in Chinese population. Methods Based on convenient sampling method, 58 imported canned foods were collected in 2022, and the contents of furan were determined by isotope dilution headspace-gas chromatography-mass spectrometry method. Combined with the food consumption of Chinese residents from 2018 to 2020, the risk of dietary exposure to furan in Chinese population was assessed by semi-quantitative assessment method. Results The detection rates of furan, 2-methylfuran and 3-methylfuran in canned meat products were 50%, 100% and 87.5%, and the corresponding average contents were 5.0ug /kg, 10.8ug /kg and 3.6ug /kg, respectively. In canned fish products, the detection rates of furan, 2-methylfuran, 3-methylfuran and 2, 5-dimethylfuran were 100%, 100%, 100% and 6%, respectively, and the corresponding average contents were 37.4 ug/kg, 52.4 ug/kg, 11.1 ug/kg and 2.5 ug/kg, respectively.. The exposure of furan to canned food was 0.4 ng/kg bw/d and the combined exposure of furan and methylfuran was 1.1 ng/kg bw/d in the population over 3 years old. The average exposure of furan and P95 to canned food was 18.5 ng/kg bw/d and 54.6 ng/kg bw/d respectively. The average combined exposure level of furan and methylfuran was 52.4 ng/kg bw/d, and the P95 exposure level was 150.8 ng/kg bw/d. For the risk of non-carcinogenic effects of furan, the exposure boundary (MOE) values of all age groups ranged from 83920 to 279494. For the carcinogenic risk of furan, the MOE values of all age groups ranged from 1717733 to 5720890. Conclusion The health risk of furan exposure from imported canned food is low in Chinese population.

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  • 收稿日期:2024-12-19
  • 最后修改日期:2025-03-26
  • 录用日期:2025-03-27
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