Objective To assess the health risk exposed to polychlorinated biphenyls （PCBs），the levels of Indicator PCBs in aquatic products in China was investigated.Methods The concentration of seven indicator PCBs （PCB 28， 52， 101， 118， 138， 153， 180） in 100 aquatic products samples，22 species in total，which were collected from 7 major producing provinces in China were analyzed by isotope dilution - gas chromatography-triple quadruped tandem mass spectrometry（GC-MS/MS）.The health risk of Chinese residents exposed to Indicator PCBs through aquatic products was assessed basing on the consumption date of aquatic products in China.Results The concentrations of the seven indicator PCBs （∑₇PCBs） in 22 species aquatic products ranged from 3.62 to 1 755.23 pg/g， which was a low level on a global scale，and all were lower than the maximum limit of aquatic products stipulated in GB 2762—2022.The concentration levels were significantly difference among species，with marine fish and crabs were significantly higher than freshwater fish， shrimp and shellfish （P<0.05）.Through fingerprint characteristics and principal component analysis，it is found that PCB 153 and PCB 138 were the main fingerprint features， and most of the samples had similar sources of contamination. The average daily dose of ∑₇PCBs in aquatic products in the six provinces ranged from 0.02×10^-7 （Liaoning） to 2.40×10^-6 mg/（kg·d） （Zhejiang）， Hazard quotient （HQ） value ranged from 0.01×10^-2 to 1.20×10^-1， and CR value ranged from 0.04×10^-7 to 4.79×10^-6.Conclusion The level and average daily dose of ∑₇PCBs in Chinese aquatic products were low.HQ values were less than 1， indicating low non-carcinogenic risk. At the median pollution level， the carcinogenic risk value of ∑₇PCBs in aquatic products in Fujian Province was 1.79×10^-6， which exceeded 1.0×10^-6， indicating a certain carcinogenic risk.