某地区孕产妇单核细胞增生李斯特菌病调查、临床特征及对分娩的影响
作者:
作者单位:

1.山西医科大学汾阳学院,山西 汾阳 032200;2.华北理工大学附属医院,河北 唐山 063000;3.孝义市疾病预防控制中心,山西 孝义 032300;4.山西省汾阳医院,山西 汾阳 032200

作者简介:

杨瑞 女 讲师 研究方向为临床营养 E-mail:ccbaob520@163.com
李建民 男 主任医师 研究方向为慢性病保健 E-mail:lijianming@163.com

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中图分类号:

R155

基金项目:

吕梁市市级课题(2020ZDSYS15)


Investigation, clinical characteristics and impact on delivery of Listeria monocytogenes disease in pregnant women in a certain region
Author:
Affiliation:

1.Department of Nursing, Fenyang College, Shanxi Medical University, Shanxi Fenyang 032200, China;2.Affiliated Hospital of North China University of Technology, Hebei Tangshan 063000, China;3.Shanxi Xiaoyi Disease Prevention and Control Center, Shanxi Xiaoyi 032300, China;4.Shanxi Fenyang Hospital, Shanxi Fenyang 032200, China

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    摘要:

    目的 探究某地区孕产妇单核细胞增生李斯特菌病的临床感染特征及分娩情况,并对感染病例开展危险因素调查确定高危食品及危险因素,为临床诊治和改善妊娠结局提供资料。方法 选取2020年5月至2023年1月某地区确诊的10例单核细胞增生李斯特菌病孕产妇进行回顾性研究,对单核细胞增生李斯特菌病进行调查,并对病例临床特征、妊娠结局的影响进行分析总结。结果 10名孕产妇发病前曾食用过冰箱内存放的水果、过夜饭菜及各类凉拌菜;10名孕产妇家中环境样本检测结果显示,涂抹样本共检出18株单核细胞增生李斯特菌,主要来源于厨房菜板、冰箱内食物。10例孕产妇感染病例的孕周16~38周,平均(27.10±7.09)周,9例出现发热症状,8例胎动减少,并伴有腹痛、恶心等消化道症状。10例单核细胞增生李斯特菌病孕产妇中,1例胎死宫内,2例流产,3例早产,4例足月,85.71%(6/7)新生儿出现单核细胞增生李斯特菌感染。结论 孕产妇单核细胞增生李斯特菌病常发生在妊娠中晚期,与孕产妇饮食习惯、食物及环境交叉感染有关,孕产妇感染单核细胞增生李斯特菌后不具有特征性临床表现,抗感染后仍会出现不良妊娠结局,且可能会引起新生儿感染;应加强单核细胞增生李斯特菌病健康宣教,提升孕产妇对该病的警惕度及重视度,防控单核细胞增生李斯特菌病。

    Abstract:

    Objective To explore the clinical infection characteristics and delivery status of Listeriosis monocytogenes in pregnant women in a certain region, and to investigate the risk factors of infection cases to identify high-risk foods and risk factors, providing information for clinical diagnosis and treatment and improving pregnancy outcomes.Methods A retrospective study was conducted on 10 cases of Listeriosis monocytogenes confirmed in a certain region from May 2020 to January 2023. The study investigated Listeriosis monocytogenes and analyzed the clinical characteristics and pregnancy outcomes of the cases.Results Ten pregnant women had consumed fruits stored in the refrigerator, overnight meals, and various cold dishes before the onset of illness. The results of environmental sample testing in the homes of the 10 pregnant women showed that a total of 18 strains of Listeriosis monocytogenes were detected in the smear samples, mainly from kitchen chopping boards and food in the refrigerator. The gestational weeks of the 10 pregnant women infected with Listeriosis monocytogenes ranged from 16 to 38 weeks, with an average of (27.10±7.09) weeks. Nine cases had fever symptoms, eight cases had decreased fetal movement, accompanied by abdominal pain, nausea, and other digestive symptoms. Among the 10 pregnant women with Listeriosis monocytogenes, one case of fetal death occurred in utero, two cases of miscarriage, three cases of premature delivery, four cases of full-term delivery, and 85.71% (6/7) of newborns had Listeriosis monocytogenes infection.Conclusion Listeriosis monocytogenes pregnant women often occurs in the middle and late pregnancy, and is related to maternal dietary habits, food, and environmental cross-infection. Maternal infection with listeria monocytogenes does not have characteristic clinical manifestations, and adverse pregnancy outcomes may still occur after anti-infection, which may also cause neonatal infection. Health education on listeriosis should be strengthened to raise maternal vigilance and attention to the disease, and to prevent and control listeriosis.

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杨瑞,李建民,王宇龙,李红梅,徐艳娥.某地区孕产妇单核细胞增生李斯特菌病调查、临床特征及对分娩的影响[J].中国食品卫生杂志,2024,36(5):607-612.

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  • 收稿日期:2023-04-13
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  • 在线发布日期: 2024-08-09
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