Objective To understand the contamination status， virulence gene carrying status and pulsed field gel electrophoresis （PFGE） molecular typing of Cronobacter sakazakii in food in Shanxi Province.Methods The strain was identified by Antu mass spectrometry detection system. Four virulence genes， ompX， cpa， hly and sip， were detected by fluorescent PCR， and PFGE molecular typing was performed.Results The results showed that in 1 050 samples from 2013 to 2022， 80 strains of Cronobacter sakazakii were isolated， and the total detection rate was 7.62%. The detection rates of four virulence genes were ompX 86.25%， cpa 85.00%， hly 98.75% and sip 86.25%， respectively. PFGE genotype was divided into 67 gene profiles with similarity ranging from 43.7% to 100%， showing great genetic diversity among strains.The strains of different origin and different manufacturers were scattered， and only a few strains showed genetic correlation.Conclusion The results of this study can provide data support for the risk status and typing of Cronobacter sakazakii in food from Shanxi Province， It is necessary to strengthen assessment and multi-link prevention and control.