In recent years， food poisoning caused by Listeria monocytogenes contamination in meat products at home and abroad has occurred frequently. Diseases caused by Listeria monocytogenes contamination have become a hidden danger to people’s health. As a traditional country in the production and consumption of meat products， China should be vigilant. Meat product manufacturers need to develop monitoring programs to prevent Listeria monocytogenes contamination and control potential risks. Based on the microbial characteristics of Listeria monocytogenes， the possible ways of contamination by Listeria monocytogenes in the production process of meat products are analyzed， and the monitoring and disinfection plan of Listeria monocytogenes in the production process of meat products is put forward， which provides direction and help for the risk control measures of meat product manufacturers.