Objective To analyze the monitoring result of iodine deficiency disorders (IDD) in Erqi District of Zhengzhou City from 2013 to 2020. Methods Salt iodine monitoring was carried out in Erqi District of Zhengzhou City from 2013 to 2020 according to the national IDD monitoring program, at the same time, urine samples were collected from newly married women of childbearing age, pregnant women, lactating women, infants aged 0-2 and children aged 8-10, and the content of urinary iodine was determined. Results During 2013-2020, the median and mean value of salt iodine content of residents in Erqi District of Zhengzhou City were in the range of 21-39 mg/kg; the coverage rate of iodized salt was more than 90.00% except for 2017, the qualified rate of iodized salt was more than 90.00% except for 2013 and 2017, the consumption rate of qualified iodized salt was more than 90.00% except for 2013, and the non iodized salt rate in 2017 was more than 20.00%. The median of urine iodine concentration in 2016, 2017, 2019 and 2020 of newly married women of childbearing age was at the appropriate level, and the median of urine iodine concentration in 2013, 2014, 2015 and 2018 was higher than the appropriate level. The proportion of iodine deficiency was the highest in 2018 (33.33%), and the lowest in 2014 and 2015 (both 0.00%). The median of urinary iodine concentration of pregnant women from 2013 to 2020 was at an appropriate level. The proportion of iodine deficiency was the highest in 2018 (45.50%) and the lowest in 2014 (5.88%). The median of urinary iodine concentration of lactating women from 2013 to 2020 was at an appropriate level. The proportion of iodine deficiency was the highest in 2018 (38.00%) and the lowest in 2014 (0.00%). The median of urinary iodine concentration of 0-2 year-old infants from 2013 to 2020 was at an appropriate level. The proportion of iodine deficiency was the highest in 2020 (25.00%), and the lowest in 2014 and 2015 (both 0.00%). The median of urinary iodine concentration of children aged 8 to 10 in 2015, 2016, 2018, and 2019 were all at an appropriate level, and the median of urinary iodine concentration in 2013, 2014, 2017, and 2020 all exceeded the appropriate level. The proportion of iodine deficiency was the highest in 2019 (23.00%), and was the lowest in 2015 and 2017 (both 0.00%). Conclusion It is necessary to continue to carry out IDD monitoring in Erqi District of Zhengzhou City, and there was still a risk of iodine deficiency in five key groups.