Objective The epidemiological characteristics of Norovirus infection in diarrhea cases in Beijing in 2017 were analyzed to provide scientific evidence for the prevention and control of Norovirus infection. Methods The descriptive epidemiological method was used to analyze the epidemiological information of the collected diarrhea cases and the result of Norovirus detection in 35 sentinel hospitals(2 490 cases) in Beijing. Results Among the 2 490 sample, the positive rate of Norovirus was 14.30%(356/2 490), with the GⅡ genotype accounted for 87.08%(310/356). The first season and the second season were the peak of Norovirus infection (17.77%, 99/557; 20.69%, 149/720). Norovirus infection had no significant gender difference(P＞0.05), and the positive rate of Norovirus in different age groups was statistically significant different(P＜0.05), and positive rate of 15-24 age group was the highest (21.66%,81/374). The proportion of nausea (18.40%,188/1 022) and vomiting (22.87%,145/634) symptoms in Norovirus infectious cases was significantly higher than that in other diarrhea cases. Conclusion GⅡ genotype is the main infection type in diarrhea Norovirus cases monitored by sentinel hospitals, the first season is the peak of infection, and the susceptible population is the youth groups.