烟台市居民熟肉制品中亚硝酸盐膳食暴露健康风险评估
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作者单位:

(1.烟台市疾病预防控制中心, 山东 烟台 264003;2.烟台市芝罘区疾病预防控制中心, 山东 烟台 264000)

作者简介:

宫春波 男 副主任技师 研究方向为食品安全和食品卫生检验 E-mail:gongchunbo@126.com

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基金项目:

2017年烟台市科学技术发展计划项目(2017WS118)


Risk assessment for dietary exposure of nitrite in cooked-meat products in Yantai population
Author:
Affiliation:

(1.Yantai Center for Disease Control and Prevention, Shandong Yantai 264003, China;2.Yantai Zhifu District Center for Disease Control and Prevention,Shandong Yantai 264000, China)

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    摘要:

    目的 了解熟肉制品来源亚硝酸盐的暴露对烟台市居民潜在的健康风险及影响因素。方法 基于蒙特卡罗方法,拟合烟台市市售熟肉制品中亚硝酸盐含量,结合2009年中国健康与营养调查数据库中山东省熟肉类消费量和人口学数据,拟合计算膳食暴露风险概率。以食品添加剂联合专家委员会规定的亚硝酸盐的每日允许摄入量(ADI)0.07 mg/kg BW为健康指导值,采用危害商(hazard quotient,HQ) 进行风险特征描述。结果 烟台市市售熟肉制品中亚硝酸盐含量数值范围为未检出(ND)~130.00 mg/kg,均值为5.48 mg/kg,概率分布为指数分布。烟台市居民2~6、7~12、13~17、18~59、≥60岁组熟肉制品来源亚硝酸盐的日暴露量(EDI)均值分别为0.004 27、0.004 02、0.003 31、0.002 48、0.002 08 mg/kg BW,其HQ大于1的概率值分别为0.80%、0.43%、0.59%、0.12%、0.02%。全人群组的HQ最敏感因素为熟肉制品亚硝酸盐含量,其贡献率为91.1%,消费量/体重的贡献率为8.9%。各人群分组的HQ分析显示,亚硝酸盐含量、消费量/体重因素对HQ的贡献率不尽相同。结论 烟台市市售熟肉制品中亚硝酸盐含量具有导致部分人群(总体约0.05%)健康危害的风险,主要敏感因素为亚硝酸盐含量。

    Abstract:

    Objective This study aimed to assess the potential risk and influence factors of the dietary exposure of nitrite to the health of Yantai residents. Methods The content of nitrite in cooked meat products and demographic data were filtered based on Monte Carlo, and the cooked meat products consumption of residents derived from the China Health and Nutrition Survey household food inventory of Shandong collected in 2009. The hazard quotient (HQ) was used to estimate dietary exposure that was exposure daily intake (EDI) divided by the acceptable daily intake (ADI) established by the Joint FAO/WHO Expert Committee on Food Additives. Results The residue content of nitrite in cooked meat products in Yantai market was between not detected (ND) to 130.00 mg/kg and the mean was 5.48 mg/kg with a Logistic distribution. The mean exposure daily intake of sodium nitrite in cooked meat products for 2-6,7-12,3-17,8-59 and ≥60 years old groups were 0.004 27,0.004 02,0.003 31,0.002 48,0.002 08 mg/kg BW, and the possibilities of HQ higher than 1 were 0.80%, 0.43%, 0.59%, 0.12%, 0.02%, respectively. The content of nitrite in cooker meat products was the most sensitive factor for HQ value with the contribution of 91.1%, and the contribution of consumption by body weight was 8.9%. The contributions of the nitrite content and the consumption by body weight were different between each group. The content of nitrite in cooked meat products was the main sensitive factor of the dietary exposure risk. Conclusion The nitrite dietary exposure of cooked meat products of Yantai population could lead chronic toxicity to health for 0.05% of all residents. Not only the residue content of sodium nitrite in cooked meat products, but also the daily intake was the main influence factors of the dietary exposure risk.

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宫春波,王朝霞,董峰光,董桂贤,毛鑫.烟台市居民熟肉制品中亚硝酸盐膳食暴露健康风险评估[J].中国食品卫生杂志,2018,30(6):639-644.

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  • 收稿日期:2018-10-22
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  • 在线发布日期: 2019-01-23
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