Objective To investigate the contamination of foodborne pathogens in meat and meat products of Guangxi, and provide reference to the effective prevention and control of foodborne disease. Methods Five kinds of meat and meat products sold in the market were collected between 2011 and 2016 from 14 cities of Guangxi. The samples were detected for 9 kinds of foodborne pathogens according to the national standard method. Results A total of 10 927 samples were detected. The total positive rate of foodborne pathogens was 5.0%(548/10 927). The positive rates of the meat and meat products were processed meat products (33.3%, 33/99),raw livestock meat (24.5%, 73/298), raw poultry meat (24.2%, 67/277), frozen minced meat products (14.4%, 14/97) and cooked meat products (3.6%, 361/10 156). The main pathogens were Salmonlla, Staphylococcus aureus and Listeria monocytogenes. None of the Campylobacter and diarrhea Escherichia coli were found in raw poultry meat. No detection of diarrhea Escherichia coli in the processed meat products. No detection of Shigella in cooked meat products. The annual detection rate of cooked meat products was 0.9%-4.9%. Conclusion The contamination of pathogens existed in meat and meat products of Guangxi in varying degrees. And the contamination persisted for many years.