Objective To learn the status of Salmonella contamination in raw poultry sold in Henan, the serotypes and genotypes of the positive isolates were studied to provide basic data for foodborne disease traceability database in Henan. Methods Salmonella detection, serotyping and pulsed field gel electrophoresis (PFGE) molecular typing were performed by the manual for food and foodborne diseases monitoring network. Results Forty-one strains of Salmonella were detected from 165 samples and the detection rate was 24.85%(41/165). The 41 strains of Salmonella had 13 serotypes, and the dominant serotypes were Salmonella corvallis, Salmonella kentucky, Salmonella typhimurium and Salmonella dabou. Forty-one strains were divided 30 molecular patterns by Xba I digestion and pulsed field gel electrophoresis, and each pattern contained 1-5 strains with similarity ranged from 47.5%-100%. The PFGE patterns were similar in different serotypes. Conclusion The contamination of Salmonella in raw poultry was serious in Henan, the serotypes and genotypes of Salmonella were diversified, and genotypes had certain regional aggregation.