To investigate the effects of parental expose to transgenic Bt rice TT51on early physical and neurological development parameters of rats offspring.MethodsParental Wistar rats were fed with rice-based diets containing TT51, MingHui63or grocery rice for 70days prior mating, and females throughout pregnancy and lactation. Body weights of parental rats were measured weekly. Body weights of the pups on 0,4, 7,4and 21d were measured and recorded. In each dietary group, pups were assessed for physical, neuromotor, reflexologic development postnatal. ResultsCompared with MingHui63group and grocery rice group on physical, neuromotor and neurological reflex parameters in the offspring, no significant differences were observed in the TT51rice group. Furthermore, no diet-related histopathological changes were observed.ConclusionThe results of this study suggested that compared with parental rice exposure to transgenic Bt rice did not exert any effects on physical and neurological development indexes of rats offspring.