Fusarium toxins, the metabolites of trichothecenes, zearalenone and fumonisins, are widespread in cereals and their products which can cause toxic effects through oral chronic exposure to human and animals. Fusarium toxins also have specific toxic effects, such as metabolism disorders, liver toxicity, kidney toxicity, neurotoxicity, skin phototoxicity, hematopoietic toxicity and so on. Mycotoxins have been shown to have mutagenic and carcinogenic effects and some fusarium toxins can cause reproductive and developmental toxicities to human and animals. This paper reviews the reproductive and developmental toxicity of fusarium toxins on human and animal.