Objective To investigate the improvement of nutritional anemia in women treated by heme iron supplement.Methods A total of 108 female subjects with nutritional anemia(Hb<120g/L) were randomly divided into a study group receiving heme iron for 45 days and a control group.Dietary survey,physical examination and blood biochemical examination were carried before and after the trial.Results Hemoglobin levels in the study group increased from(106.43±10.48)g/L to(117.34±10.25)g/L(P<0.05).There were significant differences between the study group and control group after treatment(P<0.05).The levels of free erythrocyte protophorphyrin(FEP)in the study group dropped from(942.15±96.34)μg/L to(820.53±109.95)μg/L(P<0.05),while no significant change of serum ferritin(SF)in the study group from(25.19±6.71) ng/ml to(25.40±6.69) ng/ml(P>0.05).Conclusion The heme iron supplement is effective in the treatment of nutritional anemia in women with no serious side effect.