Oral tolerance refers to a state of active inhibition of immune response to a food antigen which has been exposed previously via oral route.With exposure to a large extent of food antigens every day,adverse immunologic reactions to an antigen only take place in a small proportion of individuals because of the existence of oral tolerance.Food allergy is one of hot topics in related fields.Establishing an animal model is a direct way to explore food allergy.Avoiding oral tolerance of an animal to ..