Diisobutyl phthalate (DiBP) is a special plasticiser often used in plastic industries, which might be migrated directly from packaging materials to food or migrated to environment through plastic products containing this material to make the air, water and soil polluted. Exposure to DiBP is in different ways including breathing, eating and contacting with skin to risk human health. The latest progress on the toxicological studies of DiBP was reviewed in this paper for providing references.