Objective To investigate the situation of drugs added illegally into health foods with three functions in our country. Method A total of 166 samples collected from the national surveillance work on health food products in 2008 were detected by UPLC-Ms/Ms (Ultra Performance Liquid Chromatograph–Mass Spectrometry). Results The overall detection rate of illegal drugs was 14.5%, and the positive rates were different significantly in six provinces. The detection rate of illegal drugs in capsule samples(33.3%)was higher than those in other sample forms. The ratio of samples combined in using drugs was 45.8% in total positive samples. Conclusion Situation of illegal drugs used in health foods was very serious, especially in certain provinces. Combining use of drugs in health food products should be concerned by food hygiene supervision departments.