40 Wistar rats which were fed high fat diet were randomized into 4 groups, 10 in each group, and were fed with Fructooligosaccharide at the dose of 0, 0\^5, 1\^5 and 2\^5 g/kg BW for 28 days. The result showed that Fructooligosaccharide reduced the level of plasma total cholesterol(TC) and triglyceride (TG). The level of TC and TG were lowered significantly than the control and all treatments at the 5%. The level of high density lipoprotein\|Cholesterol(HDL\|C) was not reduced. The paper reported that Fructooligosaccharide could reduce the level of blood lipids in rats.