Bisphenol AF （BPAF） is a kind of bisphenol A analogue. With the promulgation of the EU to ban or restricting the use of BPA in a variety of places， a large number of BPA analogues have emerged. The production of BPAF is increasing due to its excellent toughness and other characteristics. Based on a large number of BPAF laboratory studies， this paper sorts out the toxicological data of BPAF from the aspects of reproductive toxicity， developmental toxicity， endocrine toxicity， immunotoxicity， and neurotoxicity， summarizes the toxic effects of BPAF， provides ideas for scientific research， and provides policy basis for scientific management.