Poisonous mushroom poisoning is a type of acute disease with the highest mortality rate among foodborne diseases in China. It has become one of the most serious food safety problems in China. Currently， there are few reports on mushrooms that cause rhabdomyolysis. Therefore， this article reviews the relevant literature on rhabdomyolytic mushroom poisoning. And its poisoning mechanism and treatment status is analyzed to provide assistance for improving clinical diagnosis and treatment level.