Proinflammatory diet can stimulate the body to develop chronic low-grade inflammation， leading to the occurrence of chronic non-communicable diseases and the accumulation of multiple systems. The purpose of this review is to present recent research on the effects of proinflammatory diet on inflammation and multisystem diseases. It outlines six common proinflammatory diets， such as diets rich in red meat， refined grains， diets of the imbalanced ratio of omega-6 to omega-3 fatty acid or rich in trans fatty acids， fried and grilled diets， high-sugar， and high-fat diets， and the three common evaluation methods of proinflammatory diets were summarized. This article emphasized the correlation between inflammatory states induced by proinflammatory diets and multisystem diseases， and provides an essential scientific basis for formulating intervention strategies for proinflammatory diet-related diseases in the future.