Objective The market regulation administration completes the supervision of food production license enterprises through the system inspection of food production enterprise.Methods This article analyzes the internal problems of modern dairy product production enterprises through the system inspection of 26 dairy product production enterprises in Guangdong Province and finds the causes through the trend of problem risk discovery.Results Through problem rectification，strengthen the implementation of corporate responsibility and strengthen quality and safety management by regulatory administration.Conclusion The system inspection of food production enterprises is an effective measure to strengthen process monitoring，problem discovery and risk control.