Objective To assess health food production risk evaluation indices and their weights and establish a risk evaluation index system for health food production enterprises in Shandong Province.Methods The “Delphi method”combined with “literature retrieval” “brainstorming” and “expert interview” were used to establish an evaluation index system for health food production in Shandong Province.Results The system consisted of dynamic and static risk evaluation systems. The dynamic risk evaluation system comprised 7 first-level and 32 second-level indicators. The static risk evaluation system comprised 6 first-level and 18 second-level indicators.Conclusion This scientific and reliable study shows that this system can be applied for the comprehensive risk evaluation of health food enterprises in Shandong Province. The system can improve supervision efficiency. Meanwhile， enterprises can be guided to standardize manufacturing behavior and improve risk awareness.