Objective The results of follow-up evaluation of GB 2757—2012 National Food Safety Standard- Distilled Wines and Mixed Wines were analyzed to reveal the main problems in the implementation of the standard and provide the basis for revision.Methods The comments of “Normal Tracking Evaluation” section on the national food safety standard follow-up evaluation platform were collected. The data was input to the Excel 2019 software for analysis. The key issues were discussed to provide suggestions for the revision of the standard.Results 827 valid comments were received. When "no comment" was rejected， 47.95% of the comments were focused on "physicochemical indexes" including methanol and cyanide indicators. It was suggested that some other issues were worthy of attention and research， such as the microbiological risk of mixed wines， new categorization， characteristic index and physicochemical indexes.Conclusion The comments reflects the key issues in the implementation of GB 2757—2012. The revision of standards should be timely started on the basis of scientific evaluation in the future. At the same time， it is suggested that the publicity， training and consultation should be strenghtened to improve understanding and applying of the standard.