Objective To study the epidemiologic and etiologic characteristics of foodborne diarrhea in Jiangxi Province between 2018 and 2019， so as to provide a scientific reference for its prevention and control.Methods Pathogen isolation and identification of foodborne diarrhea samples from the 36 hospitals in Jiangxi Province were carried out. The data collected by National Foodborne Disease Surveillance and Report System were used to analyze the epidemiological characteristics through geographic information system technology and descriptive epidemiological method.Results A total of 5 817 cases of foodborne diarrhea were collected and 504 strains of pathogenic microorganisms were detected， with the overall detection rate at 8.67%（504/5 817）. The detection rates of Salmonella， Vibrio parahaemolyticus， diarrhogenic Escherichia coli， Shigella， Campylobacter jejuni and norovirus were 3.11% （181/5 817）， 0.46% （27/5 817）， 3.87% （225/5 817）， 0.28% （16/5 817）， 0.38% （22/5 817）， 0.58% （33/5 817）. The pathogen detection rate was the highest in the third quarter. There was statistically significant difference in the detection rates of the pathogenic microorganisms in different quarters （P<0.05）. The male-female ratio was 1.2：1， 0-19 years old group accounted for 52.14% of the total cases. There was statistically significant difference between the detection rates of 0-19 years old group （10.55%， 320 / 3 033） and that of age 20 years and older group（6.61%， 184 / 2 784）（P<0.05）. There was statistically significant difference in the detection rates between the group aged 65 and older （9.88%， 56/567） and the group aged 20-64 （5.77%， 128 / 2 217）（P<0.05）. The dining places of positive cases were mainly at home. Suspicious food was mainly mixed food followed by meat and meat products and aquatic animals and their products. Nanchang （9.56%） （92/962）， Xinyu （9.33%） （46 / 493）， Jingdezhen （9.26%） （55 / 594） had higher detection rates of pathogenic microorganisms of foodborne diarrhea， while Ganzhou （7.22%） （40 / 554） and Jian （7.02%） （29/413） had lower detection rates.Conclusion Diarrhogenic Escherichia coli and Salmonella typhimurium were the main pathogens which caused food-borne diarrhea in Jiangxi Province. The majority of patients were juveniles. The detection rates of pathogenic microorganisms showed a geographic characteristics of high in the northern and central Jiangxi， and low in the southern Jiangxi.