Objective To investigate the contamination status, serotyping and antibiotic resistance of Salmonella in raw poultry meat in Fujian Province in 2020. Methods Salmonella was isolated from 178 raw poultry meat samples according to GB 4789.4—2016, serotyping and drug resistance experiments were performed on the isolated Salmonella. Results Forty strains of bacteria were detected, with a detection rate of 22.5% (40/178). By serotyping, Salmonella typhimurium accounted for the highest proportion with a detection rate of 22.5% (9/40), followed by Salmonella kentucky and Salmonella enteritidis with the detection rate of 17.5 (7/40) and 15.0% (6/40), respectively. The results of drug resistance experiments showed that these 40 strains of Salmonella were most resistant to tetracycline with a resistance rate of 77.5% (31/40), followed by nalidixic acid and ampicillin with resistance rates of 62.5% (25/40) and 52.5% (21/40), respectively. The multiple drug resistance rate (MDR) was 52.5% (21/40). Conclusion There was a certain degree of contamination of Salmonella in the raw poultry in Fujian Province in 2020, which was mainly dominated by S. typhimurium. The situation of drug resistance was serious, and there was a high rate of multi drug resistance. Food safety risk monitoring should be enhanced to prevent the outbreaks of foodborne diseases.