Objective To analyze the monitoring results of foodborne diseases in Liaoning Province, so as to provide scientific basis for prevention and control. To analyze the monitoring result of foodborne diseases in Liaoning Province, so as to provide scientific basis for prevention and control of foodborne diseases. Methods The case of foodborne disease from foodborne disease surveillance and report system in Liaoning Province in 2014-2019 were collected. The stool samples of patients were collected for pathogen detection, and the prevalence status and causes of foodborne diseases were analyzed. The case of foodborne disease from foodborne disease surveillance and report system in Liaoning Province in 2014-2019. The stool samples of patients were collected for pathogen detection, and the prevalence status and causes of foodborne diseases were analyzed. Results In Liaoning Province, the high risk group was the age of 25-44 years group (33.38%,57 151/171 219). Cases were mainly in summer (65.35%,111 896 /171 219). The detection rate of Vibrio parahemolyticus (4.37%,867/19 845) was higher than the other pathogenic bacteria. Aquatic animals(19.86%,33 002/166 211), fruits (14.58%,24 239/ 166 211) and meat (12.59%,20 929/166 211) were the main suspected exposure foods. The most risky packaging was bulk food (41.79%, 70 941/169 743) and family was the most frequent place(70.65%,119 517/169 157). The main clinical symptoms were digestive system symptoms (98.55%,168 735/171 219) and diarrhea. In Liaoning Province, the majority risk group was the age of 25-44 years group (33.38%,57 151/171 219).Cases were mainly concentrated in summer (65.35%,111 896/171 219).The detection rate of Vibrio parahemolyticus (4.37%,867/19 845) was higher than the other pathogenic bacteria. Aquatic animals(19.86%,33 002/166 211), fruits (14.58%,24 239/166 211) and meat (12.59%,20 929/166 211) were the main suspected exposure foods. The main mode of work or packaging was bulk (41.79%,70 941/169 743) and family (70.65%,119517/169 157). The main clinical symptoms were digestive system symptoms (98.55%,168 735/171 219) and diarrhea. Conclusion Liaoning Province should further improve the monitoring and reporting network of foodborne diseases, strengthen the surveillance of foodborne diseases among high-risk group, focus on the safety of seafood consumption, especially in summer, when making bulk seafood in families, and increase food safety and health education to avoid foodborne diseases. Liaoning Province should further improve the monitoring and reporting network of foodborne diseases, strengthen the surveillance of food borne diseases among high-risk group, focus on the safety of seafood consumption, especially in summer, when making bulk seafood in families, and increase food safety and health education to avoid foodborne diseases.