Objective To understand the contamination, molecular typing and drug resistance characteristics of Cronobacter in infants and young children foods in Jiangxi Province in 2018, and to provide reference data for infants and young children foods safety supervision, and clinical medication. Methods 337 commercially available infants and young children foods were collected, Cronobacter was isolated and identified according to GB 4789.40-2016 by matrix assisted laser desorption ionization-time of flight mass spectrometry(MALDI-TOF MS). The drug resistance test was performed on isolated strains via the broth microdilution method. Pulsed field gel electrophoresis(PFGE)was used to confirm the molecular type. Results Cronobacter was not detected in 168 infants and young children formulas; 24 Cronobacter isolates were isolated from 169 infants and young children cereal-based complementary food, with a positive rate of 14.2%. There was no difference in positive rate between rural and urban samples among the four seasons. Among the 13 antibiotics tested, 24 isolates were resistant to 8 kinds of antibiotics. The highest resistance rate was cefazolin (62.5%,15/24) and trimethoprim/sulfamethoxazole (29.2%,7/24). All isolates were sensitive to ciprofloxacin and imipenem. Besides, one isolate was resistant up to seven kinds of antibiotics. The result of PFGE showed that there were 22 molecular types in these isolates, and the similarity ranged from 46.6% to 100.0%. Conclusion The contamination of Cronobacter in infants and young children foods in Jiangxi Province in 2018 was similar to that in some parts of China,Cronobacter were prevalent in cereal-based supplements for infants and young children. Cronobacter isolates were not sensitive to the first and second generation cephalosporins, and PFGE molecular type of most isolates was highly diverse.