Objective A method was established for simultaneous determination of nine N-nitrosamines in cooked meat using enhance matrix removal QuEChERS-gas chromatography-tandem mass spectrometry(GC-MS/MS).Methods The samples were extracted by enhance matrix removal QuEChERS.The analytes were separated on a HP-INNOWax quartz capillary column(30 m×0.25 mm,0.25 μm), and ionized by electron impact ion source(EI).The data were collected by multiple reaction monitoring(MRM) mode,followed by qualitative screening and quantitative analysis. Results Nine N-nitrosamines had good linearities in the range of 0.20-50.00 μg/kg, with correlation coefficients above 0.997. The detection limits of were 0.02-0.1 μg/kg. The average recoveries of the nine N-nitrosamines were 78%-120% with relative standard deviations of 3.42%-15.24%.Conclusion The QuEChERS purification combined with GC-MS/MS method was rapid, accurate and sensitive,and suitable for the determination of nine N-nitrosamines in cooked meat.