Rapid determination of 11 fungicide residues in plant foods by ultra-high performance liquid chromatography-tandem mass spectrometry with isotope internal standards
Author:
Affiliation:

(Anhui Center for Disease Control and Prevention, Anhui Hefei 230601, China)

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    Objective To establish an ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)method for rapid and simultaneous determination of 11 fungicide residues in plant foods. Methods The plant foods were extracted by acetonitrile with homogenate and high speed centrifugation and purified by QuEChERS reagent. The 11 fungicides were separated on a HSS T3 column (2.1 mm×100 mm,1.7 μm) with 0.1% formic acid water-acetonitrile as mobile phase. The identifications were performed by electrospray ionization with positive scanning mode(ESI+) under the multiple reaction monitoring (MRM), and the internal standard method was used to quantify the analytes. Results The calibration curves of the 11 kinds of fungicides showed good linearity in the concentration range of 0.1-50.0 μg/L, with the correlation coefficient (r2) above 0.999 1. The detection limit was 0.2-2.0 μg/kg. The average recoveries were between 63.1% and 116.3%, and the relative standard deviations (RSD) were less than 12.1%. Conclusion The method was simple, rapid, sensitive and accurate. It was suitable for rapid determination of various fungicides in a large number of plant foods.

    Reference
    Related
    Cited by
Get Citation

ZHAO Ziwei, LIU Bolin, XIE Ji'an, WANG Xiuli, SHAN Xiaomei. Rapid determination of 11 fungicide residues in plant foods by ultra-high performance liquid chromatography-tandem mass spectrometry with isotope internal standards[J].中国食品卫生杂志,2019,31(1):22-28.

Copy
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:November 19,2018
  • Revised:
  • Adopted:
  • Online: March 22,2019
  • Published: