Objective To preliminary assess the risk of Norovirus infections by establishing oyster-Norovirus exposure model of Beijing residents from retail to table. Methods Health risk and the influencing factors were estimated using exposure assessment model with 356 quantitative detection data point of Norovirus in oysters collected in Beijing under simulated consumption scenarios and published dose-response model derived from outbreak data. Results The contamination level of GI and GII Norovirus positive samples were 2.62×10⁴ copies/g (95%CI:3.73×10³-1.54×10⁵) and 5.02×10⁴ copies/g (95%CI:8.13×10³-2.52×10⁵). For positive histo-blood group secretor groups, the risk of consuming one raw oyster potentially contaminated with GI and GII Norovirus were 0.93 (95%CI:0.73-0.98) and 0.95 (95%CI:0.80-0.99) respectively; for negative histo-blood group secretor groups, the risk 0.37 (95%CI:0.04-0.64) and 0.57 (95%CI:0.07-0.99). The estimated risk was mainly related to the assigned contamination level for those non-detected samples with the regression coefficient of 0.49. Uncertainty analysis showed that the detection level of the method used was higher than the ID₅₀/LD₅₀, which was the main source of uncertainty. Conclusion The risk of Norovirus infections after consuming raw oyster was high for Beijing residents; increasing the sensitivity and decreasing the limit of detection could decrease the uncertainty of the risk estimation.