Objective To investigate the current situation of aerobic plate count, Staphylococcus aureus and β-lactamas in raw milk in Xinxiang. Methods Twenty-nine samples and 1 mixed sample of raw milk from 2 of 3 large-scale diary farms were separately collected once a month lasting for a year. The aerobic plate count and S.aureus were determined according to the current national food safety standard, meanwhile β-lactamas was identified by colloidal gold method. Results The median of aerobic plate count (CFU/ml) of raw milk from 3 farms was 13 000,4 450 and 130 000 respectively, all significantly lower than the limit of 2×10⁶CFU/ml in GB 19301-2010 (P＜0.01). Significant difference existed between the 3 farms(P＜0.05). When comparing with the mixed sample, the significant difference was only found in one farm (P＜0.05). The aerobic plate count changed seasonally which was higher in July and August. S.aureus contamination rates of the 3 farms were 1.1%(4/360), 16.7%(30/180)and 0.0%(0/180), respectively, with the range of 50-42 000 CFU/ml. β-lactamas could be detected in raw milk from all three farms, and the positive rate was 6.1%-10.6%. Conclusion The limit of aerobic plate count of raw milk in GB 19301-2010 was much higher than the actual level in Xinxiang. It is recommended to revise the standard limit value. There was a certain degree of S.aureus contamination in raw milk in one of the farms, and supervision should be strengthened. Furthermore, identification of the source of β-lactamas was needed, the research on the detection method of β-lactamase should also be strengthened.