To investigate the features and regular patterns of foodborne disease outbreak incidents in schools in Yunnan Province between 2010 and 2015, and to provide the countermeasure against these incidents.Methods Descriptive epidemiology was used to analyze the foodborne disease outbreak incidents in schools in Yunnan Province; the number of monthly foodborne disease outbreak incidents in 2016 was predicted by seasonal trend model. Results From 2010 to 2015, the number of foodborne disease outbreak incidents, victims and deaths in schools were 106,3 972 and 2, which accounted for 6.67%, 23.32% and 0.71% of the total outbreaks. Foodborne disease outbreak incidents were mainly distributed in the primary school and middle school of rural and township areas. The major cause was associated with toxic agents from the food of animal or plant origin and microbial contamination. The foodborne disease outbreak incidents in schools was predicted as continuous rise in 2016, and reached the peak in March, April, June and September by seasonal trend model.Conclusion The best practices to prevent and reduce the foodborne disease outbreak incidents are to standardize the operation procedures of caterers, to enhance input and management measures, to establish effective supervisory mechanisms for the catering industry, and to reinforce the education of the prevention of foodborne diseases. Seasonal trend model could be used to predict the trend of the foodborne disease outbreak incidents in schools.