To investigate the foodborne pathogenic bacteria contamination in aquatic products in Guangzhou, and provide the science base for foodborne disease surveillance.Methods The monitoring data of 1 602 aquatic products from 2006 to 2013 were analyzed for foodborne pathogenic bacteria. Results The total detection rate was 21.16%, and the detection rates of Vibrio parahaemolyticus, Vibrio vulnificus, Salmonella, Listeria monocytogenes, and Vibrio cholerae were 19.54%, 8.63%, 1.08%, 0.59% and 0.14% respectively.Conclusion The major contamination of foodborne pathogenic bacteria in aquatic products in Guangzhou was still Vibrio parahaemolyticus, but the contamination of Vibrio vulnificus, Listeria monocytogenes and Salmonella also should not been ignored.