To investigate the contamination of Staphylococcus Aureus (SA) in ready-to-eat (RTE) meat products in Guangdong Province and make a preliminary risk evaluation, which would provide scientific basis for the prevention．Methods729 RTE meat products were collected from 21 cities and Shunde district of Guangdong province by random sampling and SA testing was carried out according to the national standard. A sQMRA tool was used to make preliminary risk evaluation for SA in RTE meat products.ResultsThe prevalence of SA in RTE meat products was 3.3%, the SA concentrations were from 1 to 340 cuf/g, and the average SA concentration was 10 cuf/g. The highest prevalence of SA was found in smoked barbecue RTE meat products. The peak seasons of SA contamination were the first and the fourth season．It was estimated that about 24,2 people were infected by SA during 2013. The estimated probability of SA infection was 2.3×10-4.ConclusionThe surveillance data showed that SA were existed at different levels in RTE meat products in Guangdong Province．Preliminary risk evaluation showed the SA risk of RTE meat products was relatively high. The health inspection on RTE meat products should be strengthened．