Implying the theories of public policy and public management, using multiple methods including literature review,comparative thinking,empirical data,and inductive logic, basing on the recent researches and first hand data accumulation from practice,the paper clearly depicts the current status and problems of food safety regulation, discusses the related key issues,and draws the lessons from other countries. As policy recommendation,the paper proposes a permanent solution to improve capacity of food safety regulation in the new era.On the occasion of the major reformation of national food safety regulation system,these suggestions and comments are significant for food safety regulation in the long term.