To discuss the comprehensive assessment methods for evaluation of proficiency test results. Methods Statistical methods of Z-score, point-score-system and combination scores were used to evaluate the laboratory test results from three times and provide a general assessment. Results The pass rates that analyzed by Z-score method for the five targets were 78.1%, 93.8%, 81.2%, 90.6% and 93.8%, respectively. Using point-score-system, the pass rates of the three tests were 75%, 71.9% and 90.6%. And with combination scores, 81.2% of the laboratories showed satisfying performances. Conclusion The three evaluation methods showed advantages in different aspects and fit for the comprehensive evaluation of proficiency tests．Z-score fit for single tested substance; point-score-system was suitable for each test with multi-target substances; combination scores were competent for comprehensive assessment of each laboratory during several tests.