Determination of 3 kinds of banned nitroimidazole veterinary drug and their metabolites in milk and milk powder by liquid chromatography isotope dilution tandem mass spectrometry
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O657.63;TS252.7

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    Abstract:

    Objective A sensitive liquid chromatography-tandem mass spectrometry(LC-MS/MS) method was developed for the simultaneous determination of 3 kinds of banned nitroimidazole veterinary drug and their metabolites including metronidazole,ronidazole,dimetridazole,metronidazole-OH(the metabolite of metronidazole),and 2-hydroxymethyl-1-methyl-5-nitroimidazole(the metabolite of ronidazole and dimetridazole) in milk and milk powder.Methods The protein in samples were precipitated with acetonitrile and the...

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Chen Ruichun, Ai Lianfeng, Guo Chunhai, Wang Fengchi. Determination of 3 kinds of banned nitroimidazole veterinary drug and their metabolites in milk and milk powder by liquid chromatography isotope dilution tandem mass spectrometry[J].中国食品卫生杂志,2011,23(6):543-549.

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  • Received:April 29,2011
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