Objective A QuEChERS ultra-high-performance liquid chromatography tandem mass spectrometry analytical method for the determination of ten kinds of organophosphate esters pesticides and five kinds of carbamate pesticides in tea drinks was established. Methods The extraction solution was purified with 150 mg MgSO4, 25 mg PSA and 2.5 mg GCB, and diluted with an equal volume of ultra-pure water. After centrifugation at 1 4000 r/min at 4℃ for 10 min and the supernatant was transferred, the pesticides were separated on a Waters ACQUITY BEH C18 (2.1×100 mm, 1.7 μm) chromatographic column with gradient elution using 0.1% formate-acetonitrile and 0.1% formic acid aqueous solution. Pesticides were detected via multiple reaction monitoring mode. Results The method showed a good linear range of 5-160 μg/L (R²＞0.99). The limits of detection and limits of quantification were 0.05-5 μg/L and 0.15~15 μg/L, respectively. Mean recoveries of fifteen kinds of pesticides were 71.2%-103.2%. Intraday (n=6) and interday (n=3) relative standard deviations were 0.1%-13.8% and 0.4%-12.2%, respectively. Matrix effects were 84.1%-114.3%, and could be considered to have no matrix effect. Acephate were detected in 2 out of 43 commercial tea drinks, it suggests that pesticide residues in tea drinks may cause increased health risks for people. Conclusion The method was simple to operate, rapid, accurate, and suitable to detect fifteen kinds of pesticides in different tea drinks.