边销茶中蒽醌污染状况及其暴露风险评估
作者:
作者单位:

1.杭州医学院,浙江 杭州 310013;2.国家食品安全风险评估中心,国家卫生健康委员会 食品安全风险评估重点实验室,北京 100022

作者简介:

谢倩倩 女 硕士研究生 研究方向为食品安全风险评估 E-mail:x1991qq@163.com

通讯作者:

王茵 女 研究员 研究方向为生物活性成分与人体健康效应 E-mail:wy3333@163.com

中图分类号:

R155

基金项目:

浙江省营养学医学支撑学科建设项目(16-zc03)


Anthraquinone contamination levels and exposure risk assessment in tea for sale in border areas
Author:
Affiliation:

1.Hangzhou Medical College, Zhejiang Hangzhou, 310013, China;2.China National Center for Food Safety Risk Assessment, Key Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, Beijing 100022, China

Fund Project:

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    摘要:

    目的 了解我国边销茶中蒽醌(以9,10-蒽醌为代表)的污染状况,评估我国边销茶饮用人群的暴露水平及健康风险。方法 用气相色谱串联质谱法(GC-MS/MS)测定边销茶样品中蒽醌(以9,10-蒽醌为代表)的含量,基于2016—2017年边销茶中9,10-蒽醌食品安全风险监测数据,结合内蒙古自治区、西藏自治区、青海省居民的边销茶消费量数据,通过简单分布评估法对当地居民通过饮用边销茶蒽醌的暴露量进行估计,并与每日允许摄入量(ADI,6.8 μg/kg·BW)比较后进行风险评估。结果 141份边销茶样品中蒽醌总检出率为75.18%,平均含量为0.029 2 mg/kg,我国尚未制定茶叶中蒽醌的限量标准,以2014年欧盟法规条例(EU)No 1146/2014中规定的茶叶中蒽醌最大残留限量0.02 mg/kg作为参考,总超标率为57.45%。定型包装和散装的边销茶蒽醌超标率分别为64.63%和47.46%。简单分布评估结果显示,我国内蒙古自治区、西藏自治区和青海省饮茶者全人群每日通过边销茶摄入蒽醌的平均水平为9.37×10-4 μg/kg·BW,占ADI的0.013 8%;边销茶高消费人群的每日暴露量(P95暴露量)为3.12×10-3 μg/kg·BW,占ADI的0.045 9%。不同性别-年龄组中,45~59岁女性组每日平均暴露量和P95暴露量最高,分别为1.41×10-3和6.16×10-3 μg/kg·BW,远低于ADI值。结论 内蒙古自治区、西藏自治区和青海省居民经边销茶摄入的蒽醌对人体造成的健康风险较低,处在可接受水平。但我国边销茶中普遍存在蒽醌污染,需要进一步对茶叶中蒽醌进行溯源分析并控制污染源。另外,为积极应对欧盟等国家和地区对我国出口茶叶的蒽醌含量限定,建议相关部门研究制定茶叶中蒽醌的合理限量规定。

    Abstract:

    Objective To investigate the contamination levels of anthraquinone (9,10-anthraquinone as representative) in tea for sale in border areas in China, and to assess the exposure level and health risk of anthraquinone for residents.Methods The content of anthraquinone (9,10-anthraquinone as representative) in samples of tea for sale in border areas was determined by gas chromatography-tandem mass spectrometry (GC-MS/MS). Based on food safety risk monitoring data of 9,10-anthraquinone in tea for sale in border areas from 2016 to 2017, combined with the consumption data of tea for sale in border areas for residents in the Inner Mongolia Autonomous Region, the Tibet Autonomous Region, and Qinghai Province, the exposure level of residents to anthraquinone through the consumption of tea for sale in border areas was estimated by deterministic estimate methods. Exposure results were compared with the acceptable daily intake (ADI: 6.8 μg/kg·BW).Results Among 141 samples, the anthraquinone detection rate was 75.18%, and the average content was 0.029 2 mg/kg. Up to now, the limit standard for anthraquinone has not yet been set in China. The maximum residue levels (MRLs)of anthraquinone in tea are set at 0.02 mg/kg by European Union (EU) No 1146/2014. The total over-standard rate was 57.45%. In addition, the over-standard rate of stereotyped packaging and bulk packaging was 64.63% and 47.46%, respectively. The results of the deterministic evaluation show that the average daily exposure of anthraquinone from tea for sale in border areas of the whole population in the Inner Mongolia Autonomous Region, the Tibet Autonomous Region, and Qinghai Province in China was 9.37×10-4 μg/kg·BW, 0.013 8% of the ADI. High consumer exposure (95th percentile, P95) was 3.12×10-3 μg/kg·BW, 0.045 9% of the ADI. Among the different sex-age groups, the average daily exposure and P95 daily exposure of women in the age group of 45-59 years were the highest, which were 1.41×10-3 and 6.16×10-3 μg/kg·BW, respectively. However, neither exceeded the ADI.Conclusion The results of the exposure assessment showed that the health risk for the residents of the Inner Mongolia Autonomous Region, the Tibet Autonomous Region, and Qinghai Province due to dietary exposure to anthraquinone through tea for sale in border areas was low and at an acceptable level. As anthraquinone contamination is prevalent in tea for sale in border areas, it is necessary to identify the source of anthraquinone residue, and some effective measures should be taken to control it. In addition, to respond positively to the limits of anthraquinone content in tea from China exported to the EU and other countries, it is recommended that the relevant authorities should study reasonable limits for anthraquinone in tea as soon as possible.

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谢倩倩,宋雁,雍凌,肖潇,隋海霞,王茵.边销茶中蒽醌污染状况及其暴露风险评估[J].中国食品卫生杂志,2023,35(7):1057-1062.

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  • 收稿日期:2022-10-28
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  • 在线发布日期: 2023-11-17
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