Objective To analyze the incidence trends and epidemiological characteristics of foodborne disease outbreaks caused by poisonous wild fruits in China from 2010 to 2020 and provide a scientific basis for the prevention and control of foodborne diseases.Methods Descriptive epidemiological data of all foodborne disease outbreaks caused by poisonous wild fruits reported in China from 2010 to 2020， using data from the “National Foodborne Disease Outbreak Surveillance System” was analyzed.Results From 2010 to 2020， a total of 399 cases of food poisoning outbreaks were reported， with 1 585 poisoning cases and 7 deaths； the case fatality rate was 0.44%. The most frequent reports were in the second quarter. The number of incident reports and cases in May was the highest， accounting for 50.63%（202/399）and 42.08% （667/1 585）， respectively. Southwest， South China and Central China had the highest number of incident reports and cases， 94.49% （377/399） and 94.26% （1 494/1 585）， respectively. Guizhou， Yunnan and Sichuan Provinces had the highest number of incident reports and cases， accounting for 72.18% （288/399） and 62.65% （993/1 585）， respectively. A total of 132 cases in the families were reported， with 439 cases of illness and 6 deaths， accounting for 33.08%， 27.70%， and 85.71%， respectively. The highest proportion of reported incidents was due to Coriaria massoniana， accounting for 59.15% （236/399）， followed by C. sibirica， and M. leprae. The primary cause of the incidents was fruit misuse， accounting for 98.75%（394/399）， and 99.25% （396/399） had less than 30 patients per incident.Conclusion The situation of outbreaks caused by poisonous wild fruits was serious in China. Therefore， it is necessary to improve the monitoring and rescue abilities of primary disease control and primary medical institutions. Health education should be reinforced in high-risk areas and key population groups during the high-risk season.