Objective The quality situation and existing problems of livestock， poultry meat and its by-products and fresh eggs in Shanghai from 2018 to 2020 were analyzed.Methods Public information on the supervision and sampling of animal-derived food products by the Shanghai Municipal Market Supervision Administration from 2018 to 2020 was collected， and the information was analyzed and summarized.Results From 2018 to 2020， the intensity of random inspections of livestock， poultry meat and its by-products and fresh eggs increased by about 20% year by year， and the overall quality was basically stable and controllable. The main problem was veterinary drug residues and drug abuse.Conclusion The results of supervision and sampling inspection showed that the quality awareness of related enterprises needed to be improved， and standardized management was insufficient. Some measures and recommendations for improving the quality and safety have been proposed， such as targeted deployment of monitoring， appropriate increase of punishment， improvement of the traceability system of agricultural product， development and application of vaccines， methods of biological control.