Objective An ultra-high performance liquid chromatography-tandem mass spectrometric （UPLC-MS/MS） method was developed to quantitatively determine the six kinds of aflatoxins in dairy products by employing a novel graphene based adsorbent.Methods The samples were dissolved in water and extracted by acetonitrile. After concentrated with nitrogen， the extracts were re-dissolved in the mixture of acetonitrile and 0.1% formic acid （1∶1）， and purified by graphene adsorbent. The analytes were separated by UPLC， and detected with triple quadrupole mass spectrometer.Results The linear range was 0.05-100 ng/mL with correlation coefficients （r） above 0.998. The recoveries of aflatoxins in spiked dairy product ranged from 91.0% to 118.5% with relative standard deviations of 2.39%-6.00%. The limits of quantitation were in the range of 0.01-0.05 μg/kg.Conclusion This simple and sensitive method can be used for rapid determination of six kinds of aflatoxins in dairy products.